BEST2

Across TCGA patient cohorts, BEST2 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,298 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible BEST2-associated proteins across cancer lineages are TACC2_S1946, BIN2_S462, and SRRT_T544. Each is linked with BEST2 in more than 3 cancer types. Because this analysis shows association rather than direction, both BEST2-to-partner and partner-to-BEST2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BEST2 versus TACC2_S1946 in OV, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BEST2→partner) and Y-score (partner→BEST2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	TACC2_S1946 →	+0.740	+0.409	.003	.003	3	4
OV	BIN2_S462 →	-0.655	-0.279	.001	.004	3	4
BRCA	SRRT_T544 →	+0.581	+0.223	<.001	<.001	3	3
GBM	COL8A1 →	-1.073	-0.261	.002	.002	3	3
LSCC	FAH →	-0.334	-0.297	<.001	<.001	3	3
GBM	MYO1F →	-0.559	-0.153	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,298 associations by consensus.

BEST2 vs TACC2_S1946 — OV

Explore this scatter interactively →