BEN domain containing 3 pseudogene 1Genealiases: []
Q-omics provides the consensus-scored BEND3P1 profile across patient tissues and cancer cell-line models. BEND3P1 expression is associated with patient survival in 22 of 34 cancer types, with the highest sampling consensus in COAD. Among the 18 cancer types available for tumor–normal comparison, BEND3P1 is differentially expressed in 11, with the highest sampling consensus in HNSC. Additionally, BEND3P1 RNA expression shows 13,242 significant gene co-expression associations, with the highest sampling consensus in THYM. Together, these results highlight COAD, HNSC, and THYM as cancer lineages where BEND3P1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for BEND3P1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes BEND3P1 survival associations across molecular data types. BEND3P1 RNA expression shows survival associations in the most cancer types (22). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible BEND3P1 RNA expression–survival associations across cancer types. High BEND3P1 expression shows unfavorable associations in COAD, HNSC, DLBC, MESO and UCEC, but favorable associations in KIRC. The COAD Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .006). Together, the overview and detailed table identify COAD as the clearest survival context for BEND3P1 RNA expression.
This table summarizes BEND3P1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 11. The strongest signals are observed in HNSC for RNA.
This table ranks reproducible tumor–normal expression differences for BEND3P1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. BEND3P1 shows lower tumor expression in UCEC and KICH and higher tumor expression in HNSC, BLCA, LIHC and CHOL. The HNSC box plot shows higher BEND3P1 RNA expression in tumor versus normal tissue (log2 FC = +0.506, t-test p < 0.001).
This table shows molecular features associated with BEND3P1 in patient tissues and cancer cell lines. In patient samples, BEND3P1 shows the broadest associations at the RNA and protein expression levels, with THYM recurring as the lineage with the largest associated feature set.
