BEAN1

Across TCGA patient cohorts, BEAN1 mutation is significantly associated with the RNA expression of many other genes, with 111 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BEAN1-associated genes across cancer lineages are OR13F1, TPM3P7, and MIR302D. Each is linked with BEAN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both BEAN1-to-partner and partner-to-BEAN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR13F1 grouped by BEAN1-low versus BEAN1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BEAN1→partner) and Y-score (partner→BEAN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	OR13F1 →	+0.081	+2.868	.002	.006	3	1
UCEC	TPM3P7 →	+0.229	+3.076	.002	.003	3	1
UCEC	MIR302D →	+0.761	+3.134	<.001	.001	3	1
UCEC	RNU6-492P →	+0.242	+4.245	<.001	.006	3	1
UCEC	RNU6-698P →	+0.228	+4.245	<.001	.006	3	1
UCEC	RNA5SP387 →	+0.916	+2.833	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 111 associations by consensus.

OR13F1 by BEAN1 expression — UCEC

Explore this box plot interactively →