BEAN1

Across TCGA pan-cancer cohorts, BEAN1 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of BEAN1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where BEAN1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types BEAN1 is over-expressed in tumor, although a few such as UCEC show the opposite, repressed pattern.

THCA, LUAD, and COAD are the cancer types where BEAN1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in BEAN1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Male	III,IV	+1.427	<.001	11	view →
LUAD	Male	III,IV	+2.463	<.001	9	view →
COAD	Female	All	+0.422	<.001	9	view →
BLCA	Male	All	+0.789	.001	8	view →
KIRP	Male	All	+1.046	<.001	6	view →
UCEC	All	II,III,IV	−0.475	<.001	6	view →
CHOL	All	All	+0.941	<.001	3	view →
PRAD	All	All	+0.285	<.001	2	view →
KIRC	Male	All	+0.198	.030	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

BEAN1–THCA

Open the THCA breakdown →