BCS1L

Across TCGA patient cohorts, BCS1L protein abundance is significantly associated with the RNA expression of many other genes, with 10,752 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible BCS1L-associated genes across cancer lineages are LRCH1, ASPN, and ECM2. Each is linked with BCS1L in more than 5 cancer types. Because this analysis shows association rather than direction, both BCS1L-to-partner and partner-to-BCS1L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BCS1L versus LRCH1 in OV, with a Pearson correlation of -0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BCS1L→partner) and Y-score (partner→BCS1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	LRCH1 →	-0.512	-0.409	.002	.003	3	6
OV	ASPN →	-1.471	-0.329	<.001	<.001	3	4
OV	ECM2 →	-1.065	-0.371	.002	.005	3	4
COAD	CEP85L →	-0.483	-0.259	<.001	.001	3	4
LSCC	SYNE1 →	-0.614	-0.191	.001	.004	2	5
COAD	PDCL →	-0.432	-0.368	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,752 associations by consensus.

BCS1L vs LRCH1 — OV

Explore this scatter interactively →