BCRP5

Across TCGA pan-cancer cohorts, BCRP5 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated BCRP5 data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher BCRP5 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated BCRP5 expression acts as an unfavorable survival marker, although some lineages such as UCS and BRCA show a favorable association.

UCEC, COAD, and TGCT are the cancer types where BCRP5 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Tertile	III,IV	0.645	0.824	.008	96	view →
COAD	OS	Tertile	All	0.464	0.638	.010	42	view →
TGCT	DFS	Tertile	III,IV	0.505	1.000	.016	36	view →
CHOL	OS	Tertile	IV	0.024	0.732	.014	36	view →
READ	OS	Tertile	IV	0.077	1.000	.014	36	view →
UCS	OS	Tertile	II,III,IV	0.649	0.287	.021	34	view →
OV	DFS	Median	IV	0.304	0.557	.003	22	view →
BRCA	OS	Tertile	All	0.686	0.550	.008	19	view →
LIHC	DFS	Tertile	II,III,IV	0.247	0.450	.008	18	view →
PAAD	DFS	Tertile	All	0.412	0.215	.017	16	view →
SKCM	DFS	Tertile	III,IV	0.611	0.427	.022	12	view →
PCPG	DFS	Tertile	All	0.540	0.876	.018	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

BCRP5–UCEC (DFS)

Open the UCEC breakdown →