BCRP5

Across TCGA pan-cancer cohorts, BCRP5 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of BCRP5’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where BCRP5 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types BCRP5 is over-expressed in tumor, although a few such as THCA show the opposite, repressed pattern.

KIRC, THCA, and LUAD are the cancer types where BCRP5 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in BCRP5 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	IV	+0.165	.011	4	view →
THCA	All	All	−0.267	<.001	3	view →
LUAD	All	IV	+0.610	.036	2	view →
LIHC	Female	III,IV	+0.144	.046	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

BCRP5–KIRC

Open the KIRC breakdown →