Across TCGA patient cohorts, BCRP3 mutation is significantly associated with the RNA expression of many other genes, with 391 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BCRP3-associated genes across cancer lineages are INTS4, SEC24D, and ACSL1. Each is linked with BCRP3 in more than 1 cancer types. Because this analysis shows association rather than direction, both BCRP3-to-partner and partner-to-BCRP3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BCRP3→partner) and Y-score (partner→BCRP3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	INTS4 →	+0.407	+3.346	.008	.005	3	1
UCEC	SEC24D →	+1.017	+3.470	<.001	.003	3	1
UCEC	ACSL1 →	+0.806	+3.470	.004	.003	3	1
UCEC	PI4K2A →	+0.495	+3.362	.001	.005	3	1
UCEC	SEC13 →	+0.580	+3.459	<.001	.005	3	1
UCEC	SYVN1 →	+0.455	+3.353	.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 391 associations by consensus.

Exploration

BCRP3 survival (RNA) · tumor vs normal (RNA) · all BCRP3 data types