BCORL1

Across TCGA patient cohorts, BCORL1 mutation is significantly associated with the total protein of many other genes, with 59 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BCORL1-associated genes across cancer lineages are Caspase-7-cleavedD198, PDK1, and PEA-15. Each is linked with BCORL1 in more than 5 cancer types. Because this analysis shows association rather than direction, both BCORL1-to-partner and partner-to-BCORL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Caspase-7-cleavedD198 grouped by BCORL1-low versus BCORL1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BCORL1→partner) and Y-score (partner→BCORL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Caspase-7-cleavedD198 →	+0.910	+2.338	.002	.017	3	6
LUSC	PDK1 →	+0.123	+3.331	.035	.005	3	3
LUSC	PEA-15 →	+0.252	+2.179	.024	.035	3	3
COAD	ASNS →	+0.411	+2.459	.006	.018	3	3
UCEC	Rictor_pT1135 →	-0.061	-1.530	.020	.003	3	3
UCEC	Chk2_pT68 →	-0.149	-2.044	.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 59 associations by consensus.

Caspase-7-cleavedD198 by BCORL1 expression — COAD

Explore this box plot interactively →