BCORL1

Across TCGA pan-cancer cohorts, BCORL1 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated BCORL1 data layer compared with 13 for mutation status and 5 for mass-spec protein.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher BCORL1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated BCORL1 expression acts as an unfavorable survival marker, although some lineages such as KIRC and SCLC show a favorable association.

BLCA, KIRC, and LIHC are the cancer types where BCORL1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	DFS	Quartile	All	0.415	0.725	.001	86	view →
KIRC	DFS	Median	All	0.734	0.510	<.001	78	view →
LIHC	OS	Median	All	0.712	0.838	.001	71	view →
ACC	DFS	Median	All	0.375	0.772	<.001	53	view →
LGG	OS	Median	All	0.371	0.552	<.001	52	view →
UCEC	DFS	Tertile	All	0.507	0.685	<.001	48	view →
MESO	DFS	Quartile	All	0.322	0.582	.012	35	view →
HNSC	OS	Median	II,III,IV	0.702	0.782	.007	33	view →
KICH	OS	Median	All	0.759	0.971	.009	27	view →
COAD	DFS	Quartile	All	0.733	0.855	.007	27	view →
SCLC	OS	Tertile	II,III,IV	0.706	0.391	.019	25	view →
PAAD	OS	Median	All	0.555	0.296	.001	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

BCORL1–BLCA (DFS)

Open the BLCA breakdown →