BCORL1

Across TCGA cell cohorts, BCORL1 mutation is significantly associated with the RNA expression of many other genes, with 1,129 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible BCORL1-associated genes across cancer lineages are OR2K2, OR9G1, and PPIAL4A. Each is linked with BCORL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both BCORL1-to-partner and partner-to-BCORL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR2K2 grouped by BCORL1-low versus BCORL1-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BCORL1→partner) and Y-score (partner→BCORL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	OR2K2 →	+0.052	+3.898	<.001	.005	3	2
LUNG_SCLC	OR9G1 →	+0.015	+4.169	<.001	.001	3	2
OVARY	PPIAL4A →	+0.043	+3.077	<.001	.001	3	2
LARGE_INTESTINE	SEPTIN3 →	+1.091	+1.714	<.001	.006	3	2
LARGE_INTESTINE	KCTD17 →	+0.737	+2.043	.006	.001	3	2
LARGE_INTESTINE	TRMU →	+0.580	+1.628	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,129 associations by consensus.

OR2K2 by BCORL1 expression — LUNG_SCLC

Explore this box plot interactively →