Across TCGA patient cohorts, BCOR RNA expression is significantly associated with the protein abundance of many other proteins, with 16,267 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible BCOR-associated proteins across cancer lineages are HNRNPU, PRPF4, and ARID4B. Each is linked with BCOR in more than 6 cancer types. Because this analysis shows association rather than direction, both BCOR-to-partner and partner-to-BCOR results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BCOR→partner) and Y-score (partner→BCOR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	HNRNPU →	+0.262	+0.751	<.001	<.001	3	7
GBM	PRPF4 →	+0.233	+0.581	<.001	<.001	3	6
HNSC	ARID4B →	+0.303	+0.580	<.001	<.001	3	6
GBM	OSBPL3 →	-0.404	-0.633	<.001	<.001	3	6
GBM	BCOR_S423 →	+0.549	+0.653	<.001	<.001	3	6
GBM	BUB3 →	+0.307	+0.571	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,267 associations by consensus.

Exploration

BCOR survival (RNA) · tumor vs normal (RNA) · all BCOR data types