Across TCGA patient cohorts, BCOR mutation is significantly associated with the total protein of many other genes, with 90 significant associations in total. STAD shows the largest number of these associations.

The most reproducible BCOR-associated genes across cancer lineages are TFRC, Caspase-7-cleavedD198, and eEF2. Each is linked with BCOR in more than 3 cancer types. Because this analysis shows association rather than direction, both BCOR-to-partner and partner-to-BCOR results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BCOR→partner) and Y-score (partner→BCOR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	TFRC →	+0.535	+2.115	.029	.017	3	4
COAD	Caspase-7-cleavedD198 →	+1.207	+3.016	<.001	.018	3	4
STAD	eEF2 →	+0.345	+2.807	.003	.003	3	3
STAD	Annexin_VII →	-0.133	-3.459	.039	.004	3	3
COAD	Cyclin-E2 →	+0.234	+3.593	.020	.001	3	3
COAD	Rad50 →	-0.282	-2.974	.007	.035	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 90 associations by consensus.

Exploration

BCOR survival (RNA) · tumor vs normal (RNA) · all BCOR data types