Across TCGA cell cohorts, BCOR mutation is significantly associated with the RNA expression of many other genes, with 245 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible BCOR-associated genes across cancer lineages are FKBP6, GSTT4, and ASZ1. Each is linked with BCOR in more than 2 cancer types. Because this analysis shows association rather than direction, both BCOR-to-partner and partner-to-BCOR results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BCOR→partner) and Y-score (partner→BCOR) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	FKBP6 →	+0.091	+2.342	<.001	.008	3	3
BLOOD_Lymphoma	GSTT4 →	+0.031	+2.405	.001	.005	3	2
BREAST	ASZ1 →	+0.256	+3.898	<.001	.005	3	2
BLOOD_Leukemia	SLC35G1 →	+0.928	+3.199	.008	.007	3	2
BLOOD_Leukemia	GRIFIN →	+0.237	+3.152	<.001	<.001	3	2
SKIN	TBC1D30 →	+0.840	+3.502	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 245 associations by consensus.

Exploration

BCOR survival (RNA) · tumor vs normal (RNA) · all BCOR data types