BCLAF1

Across TCGA cell cohorts, BCLAF1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,392 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible BCLAF1-associated GO terms across cancer lineages are DNA-templated DNA replication maintenance of fidelity, Regulation of chromosome segregation, and DNA-templated DNA replication. Each is linked with BCLAF1 in more than 19 cancer types. Because this analysis shows association rather than direction, both BCLAF1-to-partner and partner-to-BCLAF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated DNA replication maintenance of fidelity grouped by BCLAF1-low versus BCLAF1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BCLAF1→partner) and Y-score (partner→BCLAF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	DNA-templated DNA replication maintenance of fidelity →	+0.101	+0.657	.001	<.001	2	20
OVARY	Regulation of chromosome segregation →	+0.111	+0.868	<.001	<.001	3	19
BONE	DNA-templated DNA replication →	+0.124	+0.630	.003	.001	3	19
UPPER_AERODIGESTIVE_TRACT	Microtubule organizing center organization →	+0.086	+0.960	<.001	<.001	3	19
OESOPHAGUS	Replication fork processing →	+0.119	+0.645	<.001	<.001	2	20
BREAST	Regulation of sister chromatid segregation →	+0.123	+0.883	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,392 associations by consensus.

DNA-templated DNA replication maintenance of fidelity by BCLAF1 expression — OESOPHAGUS

Explore this box plot interactively →