Across TCGA patient cohorts, BCL9L protein abundance is significantly associated with the RNA expression of many other genes, with 7,218 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible BCL9L-associated genes across cancer lineages are EI24, CUL5, and PAFAH1B2. Each is linked with BCL9L in more than 5 cancer types. Because this analysis shows association rather than direction, both BCL9L-to-partner and partner-to-BCL9L results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BCL9L→partner) and Y-score (partner→BCL9L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	EI24 →	+0.625	+0.485	<.001	<.001	3	6
HNSC	CUL5 →	+0.496	+0.169	.001	<.001	3	5
OV	PAFAH1B2 →	+0.501	+0.423	<.001	<.001	3	5
BRCA	REXO2 →	+0.529	+0.191	.002	.002	3	5
OV	SLC35F2 →	+0.847	+0.411	<.001	<.001	3	4
OV	MPZL2 →	+1.051	+0.410	.003	.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,218 associations by consensus.

Exploration

BCL9L survival (RNA) · tumor vs normal (RNA) · all BCL9L data types