Across TCGA patient cohorts, BCL9L mutation is significantly associated with the RNA expression of many other genes, with 7,061 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BCL9L-associated genes across cancer lineages are P4HA1, GLOD4, and CTDNEP1. Each is linked with BCL9L in more than 4 cancer types. Because this analysis shows association rather than direction, both BCL9L-to-partner and partner-to-BCL9L results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BCL9L→partner) and Y-score (partner→BCL9L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	P4HA1 →	+0.892	+3.906	<.001	<.001	3	4
STAD	GLOD4 →	+0.686	+3.712	<.001	<.001	3	4
STAD	CTDNEP1 →	+0.375	+3.923	.001	<.001	3	4
UCEC	MCUB →	+0.605	+1.519	<.001	<.001	3	4
UCEC	UBE2T →	+0.438	+1.673	.003	.006	3	4
SKCM	RPL23AP82 →	+0.502	+2.398	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,061 associations by consensus.

Exploration

BCL9L survival (RNA) · tumor vs normal (RNA) · all BCL9L data types