Across TCGA patient cohorts, BCL9L mutation is significantly associated with the total protein of many other genes, with 72 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BCL9L-associated genes across cancer lineages are GAPDH, Caspase-7-cleavedD198, and eEF2. Each is linked with BCL9L in more than 3 cancer types. Because this analysis shows association rather than direction, both BCL9L-to-partner and partner-to-BCL9L results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BCL9L→partner) and Y-score (partner→BCL9L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	GAPDH →	+0.618	+3.000	.010	.036	3	4
UCEC	Caspase-7-cleavedD198 →	+0.604	+2.415	<.001	.002	3	4
STAD	eEF2 →	+0.368	+2.459	.005	.019	3	3
STAD	FOXO3a_pS318_S321 →	-0.215	-3.169	.006	.017	3	3
COAD	INPP4B →	-0.332	-1.691	.019	.043	3	3
COAD	PAI-1 →	+0.687	+3.017	.002	.017	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 72 associations by consensus.

Exploration

BCL9L survival (RNA) · tumor vs normal (RNA) · all BCL9L data types