BCL7C

Across TCGA patient cohorts, BCL7C mutation is significantly associated with the RNA expression of many other genes, with 260 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BCL7C-associated genes across cancer lineages are MIR6803, RNU6-1144P, and RNA5SP38. Each is linked with BCL7C in more than 1 cancer types. Because this analysis shows association rather than direction, both BCL7C-to-partner and partner-to-BCL7C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR6803 grouped by BCL7C-low versus BCL7C-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BCL7C→partner) and Y-score (partner→BCL7C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR6803 →	+0.172	+4.671	<.001	.002	3	2
STAD	RNU6-1144P →	+0.455	+4.184	.006	.009	3	2
SKCM	RNA5SP38 →	+0.376	+5.867	<.001	.003	3	2
COAD	LINC02131 →	+0.315	+5.516	<.001	.004	3	2
COAD	MIR6798 →	+0.867	+6.917	<.001	<.001	3	2
UCEC	MIR4999 →	+0.494	+1.936	.002	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 260 associations by consensus.

MIR6803 by BCL7C expression — UCEC

Explore this box plot interactively →