BCL7B

Across TCGA patient cohorts, BCL7B RNA expression is significantly associated with the mutation status of many other genes, with 8,950 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BCL7B-associated genes across cancer lineages are LEPR, FAT3, and TP53. Each is linked with BCL7B in more than 3 cancer types. Because this analysis shows association rather than direction, both BCL7B-to-partner and partner-to-BCL7B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LEPR grouped by BCL7B-low versus BCL7B-high in UCEC.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BCL7B→partner) and Y-score (partner→BCL7B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	LEPR →	+2.258	+0.328	<.001	<.001	3	4
UCEC	FAT3 →	+1.513	+0.157	<.001	.002	3	4
SKCM	TP53 →	+1.774	+0.261	.003	<.001	2	4
UCEC	MUC16 →	+1.595	+0.163	<.001	<.001	3	3
UCEC	DNAH7 →	+1.450	+0.222	<.001	<.001	3	3
SKCM	HECW1 →	+2.108	+0.210	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,950 associations by consensus.

LEPR by BCL7B expression — UCEC

Explore this box plot interactively →