BCL7B

Across TCGA pan-cancer cohorts, BCL7B RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated BCL7B data layer compared with 2 for mutation status and 5 for mass-spec protein.

The strongest signal is observed in kidney chromophobe (KICH), where higher BCL7B RNA is associated with worse overall survival. In most high-consensus cancer types, elevated BCL7B expression acts as an unfavorable survival marker, although some lineages such as SKCM and SARC show a favorable association.

KICH, LGG, and CESC are the cancer types where BCL7B RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	OS	Tertile	II,III,IV	0.520	1.000	<.001	89	view →
LGG	OS	Median	All	0.739	0.880	<.001	39	view →
CESC	DFS	Tertile	II,III,IV	0.634	0.903	<.001	38	view →
UVM	DFS	Quartile	III,IV	0.338	0.880	.010	35	view →
SKCM	DFS	Median	All	0.676	0.551	.003	30	view →
SARC	OS	Quartile	All	0.810	0.555	<.001	26	view →
ACC	DFS	Quartile	All	0.223	0.786	<.001	25	view →
PAAD	OS	Tertile	II,III,IV	0.429	0.683	.014	17	view →
READ	OS	Quartile	IV	0.349	0.995	.006	17	view →
THYM	OS	Median	All	0.956	0.587	.007	14	view →
GBM	OS	Median	All	0.217	0.310	.007	12	view →
PCPG	DFS	Median	All	1.000	0.795	.001	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

BCL7B–KICH (OS)

Open the KICH breakdown →