BCL7B

Across TCGA patient cohorts, BCL7B mutation is significantly associated with the RNA expression of many other genes, with 91 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BCL7B-associated genes across cancer lineages are RNA5SP436, RPL23AP90, and MIR4727. Each is linked with BCL7B in more than 1 cancer types. Because this analysis shows association rather than direction, both BCL7B-to-partner and partner-to-BCL7B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP436 grouped by BCL7B-low versus BCL7B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BCL7B→partner) and Y-score (partner→BCL7B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP436 →	+0.470	+3.522	<.001	.003	3	2
UCEC	RPL23AP90 →	+0.469	+3.124	<.001	.001	3	1
UCEC	MIR4727 →	+0.312	+3.136	.005	.007	3	1
UCEC	RIMBP3B →	+0.020	+2.746	.002	.002	3	1
UCEC	MIR6821 →	+0.373	+2.704	.004	.004	3	1
SKCM	SNORD114-23 →	+0.513	+7.816	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 91 associations by consensus.

RNA5SP436 by BCL7B expression — UCEC

Explore this box plot interactively →