BCL7B

Across TCGA cell cohorts, BCL7B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,703 significant associations in total. CNS shows the largest number of these associations.

The most reproducible BCL7B-associated GO terms across cancer lineages are Peptidyl-glutamic acid carboxylation, Protein carboxylation, and Positive regulation of isotype switching to IgG isotypes. Each is linked with BCL7B in more than 10 cancer types. Because this analysis shows association rather than direction, both BCL7B-to-partner and partner-to-BCL7B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Peptidyl-glutamic acid carboxylation grouped by BCL7B-low versus BCL7B-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BCL7B→partner) and Y-score (partner→BCL7B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Peptidyl-glutamic acid carboxylation →	+0.082	+0.508	<.001	<.001	3	11
LUNG_NSCLC_LUAD	Protein carboxylation →	+0.082	+0.508	<.001	<.001	3	11
PANCREAS	Positive regulation of isotype switching to IgG isotypes →	+0.138	+0.629	<.001	<.001	3	10
BONE	Regulation of anaphase-promoting complex-dependent catabolic process →	+0.154	+0.500	.008	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	DNA repair-dependent chromatin remodeling →	+0.085	+0.554	<.001	<.001	3	8
CNS	Negative regulation of cell cycle checkpoint →	+0.128	+0.670	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,703 associations by consensus.

Peptidyl-glutamic acid carboxylation by BCL7B expression — LUNG_NSCLC_LUAD

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