BCL6

Across TCGA patient cohorts, BCL6 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,471 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible BCL6-associated proteins across cancer lineages are BCL6_S333, BCL6_S343, and BCL6_S457. Each is linked with BCL6 in more than 6 cancer types. Because this analysis shows association rather than direction, both BCL6-to-partner and partner-to-BCL6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BCL6 versus BCL6_S333 in GBM, with a Pearson correlation of 0.76.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BCL6→partner) and Y-score (partner→BCL6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	BCL6_S333 →	+0.542	+0.977	<.001	<.001	3	7
CCRCC	BCL6_S343 →	+1.021	+0.643	<.001	<.001	3	7
BRCA	BCL6_S457 →	+0.985	+0.833	<.001	.002	3	7
BRCA	BCL6_S404 →	+0.540	+0.739	<.001	.001	3	5
CCRCC	BCL6_S361 →	+0.583	+0.752	<.001	<.001	3	5
HNSC	NT5C3A →	-0.686	-0.758	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,471 associations by consensus.

BCL6 vs BCL6_S333 — GBM

Explore this scatter interactively →