BCL6

Across TCGA patient cohorts, BCL6 protein abundance is significantly associated with the RNA expression of many other genes, with 5,176 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible BCL6-associated genes across cancer lineages are CD9, NFE2L2, and CNOT1. Each is linked with BCL6 in more than 2 cancer types. Because this analysis shows association rather than direction, both BCL6-to-partner and partner-to-BCL6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BCL6 versus CD9 in LSCC, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BCL6→partner) and Y-score (partner→BCL6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CD9 →	+0.842	+0.282	<.001	<.001	3	2
LSCC	NFE2L2 →	+0.896	+0.305	<.001	<.001	3	2
UCEC	CNOT1 →	+0.619	+0.517	.007	.001	3	2
UCEC	HS6ST1 →	+1.332	+0.433	.004	.007	3	2
GBM	ANGPTL4 →	+1.324	+1.292	.001	.003	2	3
UCEC	FPR1 →	+1.019	+0.389	.005	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,176 associations by consensus.

BCL6 vs CD9 — LSCC

Explore this scatter interactively →