BCL3

Across TCGA patient cohorts, BCL3 protein abundance is significantly associated with the RNA expression of many other genes, with 16,707 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible BCL3-associated genes across cancer lineages are SOD2, FCGR3B, and TNFAIP2. Each is linked with BCL3 in more than 4 cancer types. Because this analysis shows association rather than direction, both BCL3-to-partner and partner-to-BCL3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BCL3 versus SOD2 in GBM, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BCL3→partner) and Y-score (partner→BCL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SOD2 →	+1.557	+0.703	<.001	<.001	3	5
LSCC	FCGR3B →	+1.233	+0.237	<.001	<.001	3	5
COAD	TNFAIP2 →	+1.898	+0.775	.001	.003	3	5
COAD	TNFSF14 →	+1.257	+0.555	.002	.007	3	4
COAD	PARP9 →	+1.395	+0.614	.002	.009	3	4
OV	C15orf48 →	+1.559	+0.624	<.001	.002	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,707 associations by consensus.

BCL3 vs SOD2 — GBM

Explore this scatter interactively →