BCL2L2-PABPN1

Across TCGA cell cohorts, BCL2L2-PABPN1 mutation is significantly associated with the mutation status of many other genes, with 531 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible BCL2L2-PABPN1-associated genes across cancer lineages are SLC25A12, B4GALT2, and PANK3. Each is linked with BCL2L2-PABPN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both BCL2L2-PABPN1-to-partner and partner-to-BCL2L2-PABPN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC25A12 grouped by BCL2L2-PABPN1-low versus BCL2L2-PABPN1-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BCL2L2-PABPN1→partner) and Y-score (partner→BCL2L2-PABPN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	SLC25A12 →	+5.014	+5.584	.003	.003	1	2
BLOOD_Lymphoma	B4GALT2 →	+5.014	+5.584	.003	.003	1	2
BLOOD_Lymphoma	PANK3 →	+6.014	+6.014	.001	.001	1	2
BLOOD_Lymphoma	CLN6 →	+4.429	+5.247	.005	.005	1	2
BLOOD_Lymphoma	KHDRBS3 →	+5.014	+5.584	.003	.003	1	2
BLOOD_Lymphoma	HMGCS2 →	+4.429	+5.247	.005	.005	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 531 associations by consensus.

SLC25A12 by BCL2L2-PABPN1 expression — BLOOD_Lymphoma

Explore this box plot interactively →