BCL2L2-PABPN1

Across TCGA pan-cancer cohorts, BCL2L2-PABPN1 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated BCL2L2-PABPN1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher BCL2L2-PABPN1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated BCL2L2-PABPN1 expression acts as an unfavorable survival marker, although some lineages such as READ and GBM show a favorable association.

KIRC, ACC, and HNSC are the cancer types where BCL2L2-PABPN1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.518	0.723	<.001	119	view →
ACC	OS	Median	All	0.410	0.818	<.001	75	view →
HNSC	DFS	Quartile	IV	0.494	0.724	<.001	69	view →
LIHC	OS	Median	All	0.383	0.621	<.001	63	view →
SKCM	DFS	Quartile	III,IV	0.218	0.665	<.001	61	view →
LUAD	OS	Median	All	0.291	0.426	<.001	54	view →
LGG	DFS	Median	All	0.301	0.473	<.001	41	view →
THCA	OS	Quartile	II,III,IV	0.744	1.000	.002	30	view →
KIRP	DFS	Median	IV	0.037	0.527	.004	24	view →
BLCA	DFS	Median	II,III,IV	0.272	0.398	.014	22	view →
PRAD	DFS	Median	All	0.837	0.930	<.001	20	view →
UVM	DFS	Quartile	III,IV	0.404	0.842	.009	19	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

BCL2L2-PABPN1–KIRC (DFS)

Open the KIRC breakdown →