BCL2L13

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, BCL2L13 mutation is significantly associated with the RNA expression of many other genes, with 700 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BCL2L13-associated genes across cancer lineages are RNY4P27, RNU6-552P, and OR2AL1P. Each is linked with BCL2L13 in more than 2 cancer types. Because this analysis shows association rather than direction, both BCL2L13-to-partner and partner-to-BCL2L13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNY4P27 grouped by BCL2L13-low versus BCL2L13-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BCL2L13→partner) and Y-score (partner→BCL2L13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRNY4P27 →+0.141+3.338.003.00433
BRCARNU6-552P →+0.354+5.259<.001.00732
BLCAOR2AL1P →+0.072+4.814<.001.00332
KIRPMIR191 →+0.324+4.967<.001.00932
STADRNU6-932P →+0.554+5.267<.001.00132
HNSCRNU6-492P →+0.478+7.954<.001.00832
Each partner links to its Q-omics profile. Showing the 6 strongest of 700 associations by consensus.

RNY4P27 by BCL2L13 expression — UCEC

Box plot of RNY4P27 in BCL2L13-low vs BCL2L13-high samples in UCEC.

Explore this box plot interactively →

Exploration