BCL11A

Across TCGA patient cohorts, BCL11A RNA expression is significantly associated with the protein abundance of many other proteins, with 19,106 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible BCL11A-associated proteins across cancer lineages are BCL11A_S608, BCL11A_S630, and BCL11A_S86. Each is linked with BCL11A in more than 7 cancer types. Because this analysis shows association rather than direction, both BCL11A-to-partner and partner-to-BCL11A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BCL11A versus BCL11A_S608 in UCEC, with a Pearson correlation of 0.68.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BCL11A→partner) and Y-score (partner→BCL11A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	BCL11A_S608 →	+1.207	+1.303	<.001	<.001	3	8
LSCC	BCL11A_S630 →	+1.469	+1.430	<.001	<.001	3	8
LSCC	BCL11A_S86 →	+1.257	+1.540	<.001	<.001	3	8
GBM	SMARCC2 →	+0.280	+0.662	<.001	.002	3	6
LSCC	SMARCE1 →	+0.255	+0.936	<.001	<.001	3	6
GBM	SMC1A →	+0.314	+0.563	<.001	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,106 associations by consensus.

BCL11A vs BCL11A_S608 — UCEC

Explore this scatter interactively →