BCL10

Across TCGA patient cohorts, BCL10 protein abundance is significantly associated with the RNA expression of many other genes, with 11,425 significant associations in total. GBM shows the largest number of these associations.

The most reproducible BCL10-associated genes across cancer lineages are SH3BGRL3, MALL, and CDH3. Each is linked with BCL10 in more than 5 cancer types. Because this analysis shows association rather than direction, both BCL10-to-partner and partner-to-BCL10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BCL10 versus SH3BGRL3 in GBM, with a Pearson correlation of 0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BCL10→partner) and Y-score (partner→BCL10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SH3BGRL3 →	+0.588	+0.290	<.001	.002	3	6
HNSC	MALL →	+0.841	+0.195	.008	.006	3	6
LUAD	CDH3 →	+1.295	+0.256	<.001	<.001	3	6
BRCA	CAP1 →	+0.500	+0.238	<.001	.001	3	6
BRCA	SERPINB8 →	+0.691	+0.275	<.001	<.001	3	5
GBM	ANXA2 →	+0.815	+0.261	.002	.002	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,425 associations by consensus.

BCL10 vs SH3BGRL3 — GBM

Explore this scatter interactively →