BCKDHB

Across TCGA patient cohorts, BCKDHB RNA expression is significantly associated with the protein abundance of many other proteins, with 15,235 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible BCKDHB-associated proteins across cancer lineages are PLEKHO2, STAB1, and MYO6. Each is linked with BCKDHB in more than 4 cancer types. Because this analysis shows association rather than direction, both BCKDHB-to-partner and partner-to-BCKDHB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BCKDHB versus PLEKHO2 in GBM, with a Pearson correlation of -0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BCKDHB→partner) and Y-score (partner→BCKDHB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PLEKHO2 →	-0.358	-0.518	<.001	<.001	3	5
GBM	STAB1 →	-0.477	-0.422	<.001	<.001	3	5
LSCC	MYO6 →	+0.534	+0.565	<.001	<.001	3	5
OV	IRF4 →	-0.641	-0.893	<.001	<.001	3	5
COAD	PPA1 →	-0.386	-0.286	.009	.002	3	4
HNSC	PRPF6 →	+0.238	+0.776	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,235 associations by consensus.

BCKDHB vs PLEKHO2 — GBM

Explore this scatter interactively →