BCKDHB

Across TCGA patient cohorts, BCKDHB protein abundance is significantly associated with the RNA expression of many other genes, with 16,268 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible BCKDHB-associated genes across cancer lineages are NCF2, LILRB2, and PPP1R18. Each is linked with BCKDHB in more than 6 cancer types. Because this analysis shows association rather than direction, both BCKDHB-to-partner and partner-to-BCKDHB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BCKDHB versus NCF2 in UCEC, with a Pearson correlation of -0.30.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BCKDHB→partner) and Y-score (partner→BCKDHB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	NCF2 →	-0.934	-0.465	.004	.001	3	7
OV	LILRB2 →	-1.194	-0.625	<.001	<.001	3	7
OV	PPP1R18 →	-0.870	-0.464	.005	.004	3	7
HNSC	CTSL →	-0.970	-0.306	<.001	<.001	3	7
OV	SERPINE1 →	-1.679	-0.422	<.001	.001	3	6
OV	CORO1C →	-0.608	-0.425	.002	.003	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,268 associations by consensus.

BCKDHB vs NCF2 — UCEC

Explore this scatter interactively →