BCKDHB

Across TCGA patient cohorts, BCKDHB protein abundance is significantly associated with the protein abundance of many other proteins, with 30,840 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible BCKDHB-associated proteins across cancer lineages are ACO2, ACAD8, and ACAT1. Each is linked with BCKDHB in more than 9 cancer types. Because this analysis shows association rather than direction, both BCKDHB-to-partner and partner-to-BCKDHB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BCKDHB versus ACO2 in GBM, with a Pearson correlation of 0.49.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BCKDHB→partner) and Y-score (partner→BCKDHB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ACO2 →	+0.585	+0.609	<.001	<.001	3	10
OV	ACAD8 →	+0.571	+0.498	<.001	.002	3	10
HNSC	ACAT1 →	+0.516	+0.453	<.001	<.001	3	10
COAD	SUCLG1 →	+0.362	+0.385	<.001	<.001	3	10
UCEC	SUCLG2 →	+0.507	+0.615	<.001	<.001	3	10
COAD	CLYBL →	+0.794	+0.594	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 30,840 associations by consensus.

BCKDHB vs ACO2 — GBM

Explore this scatter interactively →