BCCIP

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, BCCIP protein abundance is significantly associated with the RNA expression of many other genes, with 16,792 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible BCCIP-associated genes across cancer lineages are NEK2, DNA2, and GLRX3. Each is linked with BCCIP in more than 7 cancer types. Because this analysis shows association rather than direction, both BCCIP-to-partner and partner-to-BCCIP results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BCCIP versus NEK2 in LSCC, with a Pearson correlation of 0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BCCIP→partner) and Y-score (partner→BCCIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCNEK2 →+1.060+0.488<.001<.00138
BRCADNA2 →+0.636+0.325<.001<.00138
LSCCGLRX3 →+0.520+0.417<.001<.00137
UCECNCAPH →+0.734+0.236<.001<.00137
LUADCCNB1 →+0.867+0.345<.001<.00137
OVTAF5 →+0.489+0.359.003.00537
Each partner links to its Q-omics profile. Showing the 6 strongest of 16,792 associations by consensus.

BCCIP vs NEK2 — LSCC

Per-sample scatter of BCCIP vs NEK2 in LSCC (Pearson r = 0.44).

Explore this scatter interactively →

Exploration