BCCIP

Across TCGA pan-cancer cohorts, BCCIP RNA is linked to patient survival in 26 of 34 cancer types, making it the most broadly survival-associated BCCIP data layer compared with 3 for mutation status and 5 for mass-spec protein.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher BCCIP RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated BCCIP expression acts as an unfavorable survival marker, although some lineages such as LGG and READ show a favorable association.

ACC, LIHC, and UVM are the cancer types where BCCIP RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	DFS	Median	All	0.173	0.675	<.001	91	view →
LIHC	OS	Median	All	0.709	0.843	<.001	76	view →
UVM	DFS	Quartile	III,IV	0.182	0.848	<.001	64	view →
HNSC	OS	Tertile	All	0.273	0.518	<.001	63	view →
LGG	OS	Median	All	0.879	0.738	<.001	51	view →
LUAD	OS	Median	III,IV	0.509	0.794	.001	49	view →
CESC	DFS	Tertile	IV	0.294	0.879	<.001	44	view →
KIRP	DFS	Quartile	All	0.814	0.975	<.001	34	view →
CHOL	DFS	Quartile	All	0.162	0.704	.009	23	view →
SARC	OS	Tertile	All	0.634	0.840	<.001	20	view →
KICH	OS	Median	II,III,IV	0.789	0.967	.005	19	view →
READ	DFS	Tertile	IV	0.847	0.293	.014	19	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 26 lineages.

BCCIP–ACC (DFS)

Open the ACC breakdown →