BCCIP

Across TCGA patient cohorts, BCCIP mutation is significantly associated with the RNA expression of many other genes, with 2,760 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BCCIP-associated genes across cancer lineages are FGF21, OR4C9P, and RNA5SP411. Each is linked with BCCIP in more than 1 cancer types. Because this analysis shows association rather than direction, both BCCIP-to-partner and partner-to-BCCIP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FGF21 grouped by BCCIP-low versus BCCIP-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BCCIP→partner) and Y-score (partner→BCCIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FGF21 →	+0.359	+1.776	.001	.008	3	2
SKCM	OR4C9P →	+0.099	+7.485	<.001	<.001	3	2
UCEC	RNA5SP411 →	+0.956	+1.863	<.001	.003	3	2
SKCM	MTCO3P2 →	+0.324	+5.159	<.001	.007	3	2
UCEC	IMMP1L →	+0.464	+2.673	<.001	<.001	3	1
UCEC	SAA4 →	-0.898	-4.392	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,760 associations by consensus.

FGF21 by BCCIP expression — UCEC

Explore this box plot interactively →