BCCIP

Across TCGA cell cohorts, BCCIP RNA expression is significantly associated with the go_rna of many other GO terms, with 4,702 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible BCCIP-associated GO terms across cancer lineages are DNA replication initiation, Attachment of spindle microtubules to kinetochore, and Lagging strand elongation. Each is linked with BCCIP in more than 17 cancer types. Because this analysis shows association rather than direction, both BCCIP-to-partner and partner-to-BCCIP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA replication initiation grouped by BCCIP-low versus BCCIP-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BCCIP→partner) and Y-score (partner→BCCIP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	DNA replication initiation →	+0.175	+0.862	.004	.004	1	18
UPPER_AERODIGESTIVE_TRACT	Attachment of spindle microtubules to kinetochore →	+0.146	+1.058	<.001	<.001	3	16
OVARY	Lagging strand elongation →	+0.162	+0.767	<.001	<.001	3	15
BONE	Maturation of SSU-rRNA →	+0.129	+0.589	.001	.004	3	15
UPPER_AERODIGESTIVE_TRACT	RNA 5'-end processing →	+0.108	+1.082	<.001	<.001	2	16
BREAST	Double-strand break repair via synthesis-dependent strand annealing →	+0.083	+0.514	<.001	.006	2	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,702 associations by consensus.

DNA replication initiation by BCCIP expression — LUNG_NSCLC_LUSC

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