BCAT1

Across TCGA cell cohorts, BCAT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,999 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible BCAT1-associated GO terms across cancer lineages are Lactate metabolic process, Protein modification by small protein removal, and Sulfide oxidation, using sulfide:quinone oxidoreductase. Each is linked with BCAT1 in more than 8 cancer types. Because this analysis shows association rather than direction, both BCAT1-to-partner and partner-to-BCAT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Lactate metabolic process grouped by BCAT1-low versus BCAT1-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BCAT1→partner) and Y-score (partner→BCAT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Lactate metabolic process →	+0.188	+2.279	<.001	<.001	3	9
BONE	Protein modification by small protein removal →	+0.036	+1.861	.001	.003	3	9
BLOOD_Leukemia	Sulfide oxidation, using sulfide:quinone oxidoreductase →	-0.240	-1.314	.002	<.001	3	8
OESOPHAGUS	Protein K63-linked deubiquitination →	+0.062	+1.931	.003	.004	3	8
SKIN	Regulation of intracellular pH →	-0.063	-2.091	.001	.001	3	8
BREAST	Regulation of protein localization to mitochondrion →	+0.087	+1.688	.001	.002	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,999 associations by consensus.

Lactate metabolic process by BCAT1 expression — BREAST

Explore this box plot interactively →