BCAS2

Across TCGA patient cohorts, BCAS2 mutation is significantly associated with the total protein of many other genes, with 7 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BCAS2-associated genes across cancer lineages are JNK2, mTOR, and p62 Lck ligand. Each is linked with BCAS2 in more than 1 cancer types. Because this analysis shows association rather than direction, both BCAS2-to-partner and partner-to-BCAS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, JNK2 grouped by BCAS2-low versus BCAS2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BCAS2→partner) and Y-score (partner→BCAS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	JNK2 →	+0.332	+3.000	.003	.037	3	1
UCEC	mTOR →	-0.291	-3.000	.001	.037	3	1
UCEC	p62 Lck ligand →	+0.490	+3.009	.009	.019	3	1
UCEC	PEA-15_pS116 →	+0.424	+3.000	.036	.037	3	1
UCEC	STAT5a →	+0.570	+3.000	.013	.037	3	1
UCEC	Chk2 →	-0.455	-3.000	<.001	.037	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

JNK2 by BCAS2 expression — UCEC

Explore this box plot interactively →