BCAS2

Across TCGA pan-cancer cohorts, BCAS2 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of BCAS2’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where BCAS2 RNA is repressed in tumor relative to normal tissue. In most cancer types BCAS2 is over-expressed in tumor, although a few such as KICH and THCA show the opposite, repressed pattern.

KICH, THCA, and LIHC are the cancer types where BCAS2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in BCAS2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Female	II,III,IV	−1.768	<.001	9	view →
THCA	Male	III,IV	−0.632	<.001	9	view →
LIHC	Male	All	+0.628	<.001	9	view →
HNSC	Male	All	+0.346	.009	6	view →
KIRC	Male	III,IV	−0.307	.011	4	view →
CHOL	Male	All	+1.216	<.001	3	view →
BRCA	All	II,III,IV	+0.144	.022	3	view →
KIRP	Male	All	−0.511	<.001	2	view →
LUSC	Male	All	+0.314	.001	2	view →
STAD	All	II,III,IV	+0.281	.033	1	view →
LUAD	All	All	+0.167	.022	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

BCAS2–KICH

Open the KICH breakdown →