BCAS2

Across TCGA cell cohorts, BCAS2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,197 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible BCAS2-associated GO terms across cancer lineages are Telomeric 3' overhang formation, Positive regulation of centriole replication, and Regulation of centriole replication. Each is linked with BCAS2 in more than 16 cancer types. Because this analysis shows association rather than direction, both BCAS2-to-partner and partner-to-BCAS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Telomeric 3' overhang formation grouped by BCAS2-low versus BCAS2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BCAS2→partner) and Y-score (partner→BCAS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Telomeric 3' overhang formation →	+0.155	+1.042	<.001	<.001	3	17
BLOOD_Myeloma	Positive regulation of centriole replication →	+0.120	+1.096	.005	.002	2	15
BLOOD_Lymphoma	Regulation of centriole replication →	+0.072	+0.905	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Protein localization to kinetochore →	+0.126	+0.852	.002	<.001	3	12
UPPER_AERODIGESTIVE_TRACT	DNA replication initiation →	+0.168	+1.002	<.001	<.001	3	12
OVARY	Kinetochore organization →	+0.105	+0.647	.007	.002	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,197 associations by consensus.

Telomeric 3' overhang formation by BCAS2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →