BCAR4

Across TCGA patient cohorts, BCAR4 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BCAR4-associated genes across cancer lineages are RNU6-73P, RN7SKP112, and NDUFA5P1. Each is linked with BCAR4 in more than 1 cancer types. Because this analysis shows association rather than direction, both BCAR4-to-partner and partner-to-BCAR4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-73P grouped by BCAR4-low versus BCAR4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BCAR4→partner) and Y-score (partner→BCAR4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-73P →	+0.519	+6.226	<.001	.001	3	1
UCEC	RN7SKP112 →	+0.250	+5.186	.001	.007	3	1
UCEC	NDUFA5P1 →	+0.269	+5.420	<.001	.005	3	1
UCEC	LINC01216 →	+0.134	+5.852	<.001	.003	3	1
UCEC	MIR3158-1 →	+0.802	+5.299	<.001	.006	3	1
UCEC	MIR4752 →	+0.750	+9.066	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

RNU6-73P by BCAR4 expression — UCEC

Explore this box plot interactively →