BCAR3

Across TCGA patient cohorts, BCAR3 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,970 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible BCAR3-associated proteins across cancer lineages are BCAR3_S338, BCAR3_S290, and BCAR3_S317. Each is linked with BCAR3 in more than 8 cancer types. Because this analysis shows association rather than direction, both BCAR3-to-partner and partner-to-BCAR3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BCAR3 versus BCAR3_S338 in BRCA, with a Pearson correlation of 0.81.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BCAR3→partner) and Y-score (partner→BCAR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	BCAR3_S338 →	+1.106	+1.512	<.001	<.001	3	9
OV	BCAR3_S290 →	+0.727	+0.820	<.001	<.001	3	8
OV	BCAR3_S317 →	+0.772	+0.703	<.001	<.001	3	6
LSCC	BCAR3_S370 →	+0.878	+0.918	<.001	<.001	3	6
HNSC	BCAR1_S639 →	+0.473	+0.687	<.001	.002	3	5
LSCC	BCAR1 →	+0.282	+0.601	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,970 associations by consensus.

BCAR3 vs BCAR3_S338 — BRCA

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