BCAR3

Across TCGA patient cohorts, BCAR3 mutation is significantly associated with the RNA expression of many other genes, with 2,983 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible BCAR3-associated genes across cancer lineages are OR8A1, IGHD2-15, and TPRKB. Each is linked with BCAR3 in more than 2 cancer types. Because this analysis shows association rather than direction, both BCAR3-to-partner and partner-to-BCAR3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR8A1 grouped by BCAR3-low versus BCAR3-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BCAR3→partner) and Y-score (partner→BCAR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	OR8A1 →	+0.253	+2.362	.006	.007	3	3
UCEC	IGHD2-15 →	+1.080	+1.705	<.001	<.001	3	3
BLCA	TPRKB →	+0.584	+3.235	<.001	.008	3	2
BLCA	CD96 →	+1.134	+3.343	.003	.005	3	2
BLCA	RNU6-1084P →	+0.133	+3.373	<.001	.004	3	2
KIRP	RNA5SP421 →	+0.204	+5.539	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,983 associations by consensus.

OR8A1 by BCAR3 expression — BLCA

Explore this box plot interactively →