BCAR3

Across TCGA cell cohorts, BCAR3 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,419 significant associations in total. BONE shows the largest number of these associations.

The most reproducible BCAR3-associated GO terms across cancer lineages are Regulation of hemostasis, Regulation of blood coagulation, and Urokinase plasminogen activator signaling pathway. Each is linked with BCAR3 in more than 14 cancer types. Because this analysis shows association rather than direction, both BCAR3-to-partner and partner-to-BCAR3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of hemostasis grouped by BCAR3-low versus BCAR3-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BCAR3→partner) and Y-score (partner→BCAR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Regulation of hemostasis →	+0.237	+2.651	.001	<.001	3	15
LUNG_NSCLC_LUSC	Regulation of blood coagulation →	+0.236	+2.651	.001	<.001	3	15
LIVER	Urokinase plasminogen activator signaling pathway →	+1.239	+2.338	<.001	<.001	3	14
BONE	Hemostasis →	+0.096	+2.946	<.001	<.001	3	14
LIVER	Regulation of calcium ion transport into cytosol →	+0.322	+2.842	<.001	<.001	3	13
BONE	Regulation of vasculature development →	+0.114	+3.164	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,419 associations by consensus.

Regulation of hemostasis by BCAR3 expression — LUNG_NSCLC_LUSC

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