BCAR3

Across TCGA cell cohorts, BCAR3 mutation is significantly associated with the RNA expression of many other genes, with 68 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible BCAR3-associated genes across cancer lineages are OR10R2, IL3, and PRAMEF10. Each is linked with BCAR3 in more than 1 cancer types. Because this analysis shows association rather than direction, both BCAR3-to-partner and partner-to-BCAR3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10R2 grouped by BCAR3-low versus BCAR3-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (BCAR3→partner) and Y-score (partner→BCAR3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR10R2 →	+1.495	+3.966	<.001	.001	3	2
LUNG_SCLC	IL3 →	+0.055	+5.029	<.001	.006	3	1
LUNG_SCLC	PRAMEF10 →	+1.180	+5.643	<.001	.002	3	1
LUNG_SCLC	PRAMEF17 →	+0.013	+5.643	<.001	.002	3	1
LUNG_SCLC	SPINK8 →	+0.513	+5.029	<.001	.006	3	1
LUNG_SCLC	PRAMEF33 →	+0.649	+5.029	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 68 associations by consensus.

OR10R2 by BCAR3 expression — BLOOD_Leukemia

Explore this box plot interactively →