BCAN

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, BCAN protein abundance is significantly associated with the protein abundance of many other proteins, with 11,157 significant associations in total. GBM shows the largest number of these associations.

The most reproducible BCAN-associated proteins across cancer lineages are ABCA1, AKAP12_T1116, and AMPH. Each is linked with BCAN in more than 1 cancer types. Because this analysis shows association rather than direction, both BCAN-to-partner and partner-to-BCAN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, BCAN versus ABCA1 in UCEC, with a Pearson correlation of -0.45.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (BCAN→partner) and Y-score (partner→BCAN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECABCA1 →-0.435-0.990<.001<.00132
UCECAKAP12_T1116 →+1.063+1.037.001<.00132
UCECAMPH →+0.725+0.805<.001<.00132
UCECAP3B2 →+1.283+0.959<.001.00232
UCECAPBB1 →+0.652+0.947<.001<.00132
GBMRCSD1_S268 →-0.813-0.654<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,157 associations by consensus.

BCAN vs ABCA1 — UCEC

Per-sample scatter of BCAN vs ABCA1 in UCEC (Pearson r = -0.45).

Explore this scatter interactively →

Exploration