BCAN

Across TCGA pan-cancer cohorts, BCAN RNA is linked to patient survival in 23 of 34 cancer types, making it the most broadly survival-associated BCAN data layer compared with 11 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher BCAN RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated BCAN expression acts as an unfavorable survival marker, although some lineages such as LGG and GBM show a favorable association.

LUAD, MESO, and LAML are the cancer types where BCAN RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Tertile	All	0.702	0.841	<.001	83	view →
MESO	OS	Quartile	All	0.266	0.586	<.001	65	view →
LAML	DFS	Median	All	0.250	0.515	<.001	54	view →
LGG	OS	Median	All	0.939	0.846	<.001	44	view →
SKCM	OS	Median	III,IV	0.275	0.515	<.001	39	view →
GBM	DFS	Median	All	0.392	0.174	<.001	24	view →
KIRC	DFS	Quartile	All	0.743	0.917	.002	22	view →
ACC	DFS	Tertile	All	0.270	0.668	.005	20	view →
KIRP	DFS	Tertile	All	0.849	0.966	<.001	19	view →
DLBC	DFS	Median	IV	0.412	1.000	.006	18	view →
ESCA	DFS	Quartile	III,IV	0.259	0.506	.006	12	view →
BLCA	OS	Median	III,IV	0.164	0.407	.019	11	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 23 lineages.

BCAN–LUAD (DFS)

Open the LUAD breakdown →