BCAN

Across TCGA cell cohorts, BCAN RNA expression is significantly associated with the go_rna of many other GO terms, with 3,253 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible BCAN-associated GO terms across cancer lineages are Aldosterone biosynthetic process, Mineralocorticoid biosynthetic process, and Mineralocorticoid metabolic process. Each is linked with BCAN in more than 6 cancer types. Because this analysis shows association rather than direction, both BCAN-to-partner and partner-to-BCAN results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Aldosterone biosynthetic process grouped by BCAN-low versus BCAN-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (BCAN→partner) and Y-score (partner→BCAN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Aldosterone biosynthetic process →	+0.884	+0.630	<.001	<.001	3	7
SOFT_TISSUE	Mineralocorticoid biosynthetic process →	+0.900	+0.620	<.001	<.001	3	7
SOFT_TISSUE	Mineralocorticoid metabolic process →	+1.128	+0.896	<.001	<.001	3	7
BREAST	Nucleoside triphosphate biosynthetic process →	+0.060	+0.203	.005	.003	3	7
BREAST	Ribonucleoside triphosphate biosynthetic process →	+0.067	+0.199	.001	.003	3	7
SKIN	Catecholamine transport →	+0.348	+1.653	.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,253 associations by consensus.

Aldosterone biosynthetic process by BCAN expression — SOFT_TISSUE

Explore this box plot interactively →